Bioengineered salivary gland could treat xerostomia

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Functional salivary gland regeneration by transplantation of a bioengineered organ germ

Salivary gland hypofunction, also known as xerostomia, occurs as a result of radiation therapy for head cancer, Sjögren's syndrome or aging, and can cause a variety of critical oral health issues, including dental decay, bacterial infection, mastication dysfunction, swallowing dysfunction and reduced quality of life. Here we demonstrate the full functional regeneration of a salivary gland that ...

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ژورنال

عنوان ژورنال: British Dental Journal

سال: 2013

ISSN: 0007-0610,1476-5373

DOI: 10.1038/sj.bdj.2013.1012